British Air Force Typhoon FGR4s have operated alongside French warplanes in a joint strike on an underground arms cache in Syria operated by the IS group, per a report from the British defence ministry.
The site, located using surveillance, was thought to be containing munitions and bombs, the announcement noted, and was located in mountainous terrain just above the ancient city of Palmyra in Syria's central region.
"The RAF jets utilized Paveway IV guided bombs to hit a series of access tunnels providing entry to the site... early reports suggest the objective was successfully hit," the MoD said.
There was no sign of any civilian casualties in the operation conducted Saturday night and all the aircraft returned to base without incident, the defence officials confirmed.
The Typhoon fighters were supported by a Voyager refuelling tanker.
IS - alternatively referred to as the so-called Islamic State - enforced militant control over parts of Syria and Iraq before its territorial defeat in 2019.
"This action underscores the UK's leading role, and resolve to operate in unison with our allies, to eradicate any re-emergence of Daesh and their dangerous and violent ideologies in the area," the British Defence Secretary John Healey stated.
RAF aircraft have performed overwatch operations over Syria to "prevent any efforts to regroup" of Islamic State subsequent to its defeat at the battle of Baghuz in the year 2019, the ministry said.
"I must thank the personnel of the UK armed forces involved in this mission for their skill and their bravery," the Defence Secretary said. "They were among numerous British personnel on duty over the festive period. This mission, to eliminate militants who pose a risk to our safety, shows how British military are always on standby, throughout the year, keeping Britain secure domestically and strong abroad."
Last December, the US military conducted what it termed a "large-scale strike" on Islamic State objectives in the country, subsequent to an assault resulted in the deaths of two US servicemembers and a civilian interpreter in the Palmyra area.
The UN reports Daesh still maintains roughly 5-7 thousand militants in Syria and Iraq.